Memantine
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Neuro Drugs
- Anticholinergic Syndrome
- Cholinergic Crisis
- Benztropine / Trihexyphenidyl
- Pyridostigmine, Neostigmine, Edrophonium
- Donepezil
- Memantine
- Scopolamine
- Levodopa, Carbidopa
- Selegiline / Rasagiline
- Entacapone / Tolcapone
- Propofol
- Halothane / Flurane
- Opioids
- Succinylcholine
- Lidocaine
- Ergotamine
- Triptans
- Pregabalin
- Gabapentin
- Ramelteon
Memantine
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Summary
Memantine is a medication that is used to treat Alzheimer Disease. This medication offers a symptomatic benefit by improving the cognition of patients, but cannot cure nor reverse the course of disease.
Key Points
- Memantine (Namenda)
- Mechanism
- NMDA receptor antagonist
- Binds to NMDA receptors, blocking the neurotransmitter glutamate which then prevents calcium from building up in the brain cells.
- NMDA receptor antagonist
- Clinical Uses
- Alzheimer Disease
- Memantine is not a cure, but slows the progression of the disease
- Alzheimer Disease
- Side Effects and Adverse Reactions
- Stevens Johnson Syndrome
- Report symptoms of a rash immediately
- Sedation, drowsiness
- Dizziness
- Constipation
- Headaches
- Stevens Johnson Syndrome
- Mechanism