Hemangioblastoma

Summary

Hemangioblastomas are vascular brain tumors mainly localized to the cerebellum. We typically find them in adults, as well as children who have Von Hippel-Lindau Syndrome. The presence of hemangioblastomas can cause an increase in the hormone erythropoietin, which often leads to secondary polycythemia. A biopsy will reveal a highly vascular tumor with a foam-like appearance. 

Key Points

• Hemangioblastoma
  • Characteristics
    • Brain tumor originating from blood vessels
  • Location
    • Most often cerebellar in origin
  • Presentation
    • Typically presents in adults
    • Seen in children with Von Hippel-Lindau Syndrome (VHL)
      • Hemangioblastomas affecting retina and CNS
    • Can produce erythropoietin (EPO)
      • Leads to secondary polycythemia (high RBC count)
  • Histology
    • Highly vascular tumor on biopsy