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Retrovirus

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Key Points

  • Retroviruses
    • Characteristics
      • RNA viruses
        • replicate in the nucleus of cells
          • unlike most RNA viruses, which replicate in the cytoplasm
        • Single-stranded
      • + sense
      • Linear chromosome
      • 2 copies of genome (diploid)
      • Enveloped
      • Capsid is icosahedral (HTLV) or conical (HIV)
      • possesses reverse transcriptase
  • Medical importance