USMLE

Acute T-Cell Leukemia/Lymphoma (ATLL)

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Leukemias and Lymphomas
  1. Acute Myelogenous Leukemia (AML)
  2. Acute Promyelocytic Leukemia (APL)
  3. Acute Lymphocytic Leukemia (ALL)
  4. Chronic Myelogenous Leukemia (CML)
  5. Chronic Lymphocytic Leukemia (CLL)
  6. Hairy Cell Leukemia (HCL)
  7. Hodgkin Lymphoma
  8. Burkitt Lymphoma
  9. Diffuse Large B Cell Lymphoma (DLBCL)
  10. Follicular Lymphoma
  11. Mantle Cell Lymphoma
  12. Marginal Zone Lymphoma
  13. Primary CNS Lymphoma (PCNSL)
  14. Acute T-Cell Leukemia/Lymphoma (ATLL)
  15. Mycosis Fungoides / Sezary Syndrome

Summary

Acute T-Cell Leukemia and Lymphoma, or ATLL for short, is a cancer of T-cells which can be present in the bloodstream as leukemia, or form masses in lymph nodes as lymphoma. This condition is associated with the HTLV-1 or human T-lymphotropic virus type I, a virus that is part of the retrovirus family. The cancer is most commonly seen in adults from areas where HTLV-1 is endemic, including Japan, West Africa, and the Caribbean. Besides the classic symptoms of leukemia and lymphoma, one high-yield clinical finding is the development of red scaly rashes.