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B-Cell Activation

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  • B-cell Activation
    • Upon antigen binding to B-cell receptors, the B-cell:
      • (1) endocytoses the antigen, then breaks it down into smaller fragments
      • (2) presents the antigen fragments on its surface to helper T cells.
      • (3) Helper T-cells release cytokines (signaling molecules) to activate the B-cell
      • (4) Activated B-cell then proliferates and turns into plasma or memory cells (see video)