Plasma B-Cells
1,265 views
Immunology
- Innate Immunity
- Adaptive Immunity
- Macrophages
- Neutrophils
- Dendritic Cells
- Mast Cells
- Eosinophils
- Basophils
- Natural Killer Cells
- Antigens
- MHC I and II
- Antibodies
- B Lymphocytes Overview
- B Cell Stages
- B-Cell Activation
- Plasma B-Cells
- Memory B-Cells
- T-Lymphocytes Overview
- T-Cell Stages
- Types of Activated T-Cells
Summary
When B-cells are activated by antigen binding, they differentiate into either plasma or memory B-cells. Plasma B-cells are short-lived and reside in the bone marrow, where they produce large quantities of antibody proteins that mark pathogens for destruction.
Key Points
- Plasma B cells
- Short-lived
- Secrete antibodies in vast amounts during an infection
- Main effector of the humoral immune response.
- Marks pathogen for phagocytosis by innate immune cells
- Initiates complement system
- Attaches to mast cells to release inflammatory chemicals