USMLE

Pepsin

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Digestive
  1. Gastrin
  2. Pepsin
  3. Amylase
  4. Lipase
  5. Trypsin
  6. CCK
  7. Secretin
  8. GI System
  9. Ingestion
  10. Liver
  11. Bile
  12. Exocrine Pancreas
  13. Endocrine Pancreas
  14. Small Intestine
  15. Large Intestine
  16. GI Nervous Control
  • Pepsin
    • The main digestive enzyme produced in the stomach
      • Specific enzyme in a wider class of protein-degrading enzymes, called proteolytic enzymes/proteases/peptidases
    • Secreted by chief cells in the stomach as the precursor pepsinogen 
    • Activated by HCl (gastric acid)
    • Catalyzes the breakdown of proteins by hydrolyzing peptide bonds