USMLE

RAAS System

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Renal
  1. Renin
  2. Angiotensin II
  3. Aldosterone
  4. ADH
  5. RAAS System
  6. Kidney Overview
  7. Nephron Structure
  8. Glomerulus
  9. Proximal Tubule
  10. Loop of Henle
  11. Distal Tubule
  12. Collecting Duct
  • Renin-Angiotensin-Aldosterone System (RAAS) 
    • Main purpose is to regulate blood pressure by modulating the kidney's reabsorption of water and salt
      • Occurs through a network of sensors and effector hormones (angiotensin II, aldosterone, and antidiuretic hormone)
    • The enzyme renin cleaves precursor hormone angiotensinogen to form angiotensin I
    • Angiotensin-converting enzyme (ACE) then cleaves angiotensin I to form angiotensin II
    • Angiotensin II induces release of hormones aldosterone and ADH