Vitamin B3 (Niacin) Biochemistry
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Vitamin B3 (Niacin) Biochemistry
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Vitamin B3, also known as niacin, is a water-soluble vitamin which serves a key role as a precursor of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Found in foods, it is also used pharmacologically as a treatment for lipid disorders, specifically for its ability to raise HDL (good cholesterol) and lower VLDL and LDL (bad cholesterol). Its synthesis requires a number of factors: tryptophan, vitamin B2 (riboflavin), and vitamin B6 (pyridoxine).