Vitamin B5 (Pantothenic Acid)
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Vitamins
- Vitamin B1 (Thiamine) Biochemistry
- Vitamin B1 (Thiamine) Deficiency
- Vitamin B2 (Riboflavin)
- Vitamin B3 (Niacin) Biochemistry
- Vitamin B3 (Niacin) Deficiency and Excess
- Hartnup Disease
- Vitamin B5 (Pantothenic Acid)
- Vitamin B6 (Pyridoxine)
- Vitamin B7 (Biotin)
- Vitamin B9 (Folate)
- Vitamin B12 (Cobalamin) Biochemistry
- Vitamins B9 and B12 Deficiencies
- Vitamin A (Retinol) Biochemistry
- Vitamin A (Retinol) Deficiency and Excess
- Vitamin C (Ascorbic Acid) Biochemistry
- Vitamin C (Ascorbic Acid) Deficiency and Excess
- Vitamin D Biochemistry
- Vitamin D Deficiency and Excess
- Vitamin E (Tocopherol/Tocotrienol)
- Vitamin K Biochemistry
- Vitamin K Deficiency
- Zinc
- Kwashiorkor and Marasmus
Vitamin B5 (Pantothenic Acid)
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Summary
Vitamin B5 (Pantothenic Acid) is a water-soluble vitamin which serves a key role in the synthesis of CoA (coenzyme A), a cofactor in many metabolic reactions. It is also plays a role in fatty acid synthesis, as it is a cofactor for the enzyme fatty acid synthase (FAS). Vitamin B5 Deficiency is rare, and primarily presents with symptoms of gastroenteritis (diarrhea), with possible adrenal insufficiency, dermatitis, or alopecia.
Key Points
- Vitamin B5 (Pantothenic Acid)
- Essential cofactor for:
- coenzyme A (CoA)
- cofactor for acyl transfers
- key role in first step of TCA cycle (oxaloacetate to citrate)
- fatty acid synthase
- coenzyme A (CoA)
- Essential cofactor for:
- Deficiency (low yield)
- rare, seen in the severely malnourished
- enteritis/GI distress
- dermatis, alopecia, and adrenal insufficiency also seen
- rare, seen in the severely malnourished
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