Vitamin B1 (Thiamine) Biochemistry

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Thiamine (Vitamin B1) is a water-soluble vitamin and an important constituent of TPP (thiamine pyrophosphate), a cofactor found in several important dehydrogenase reactions.

Specifically, TPP is an important cofactor for pyruvate dehydrogenase (see Pyruvate Metabolism), α-ketoglutarate dehydrogenase, and branched-chain ketoacid dehydrogenase (see Maple Syrup Urine Disease). Besides dehydrogenase reactions, TPP also serves an important role as a cofactor for transketolase.

Find Thiamine Biochemistry and other Vitamins among Pixorize's visual mnemonics for the USMLE Step 1 and NBME shelf exams.