Medicine & USMLE

Canagliflozin (Old)

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Canagliflozin is a medication used to lower blood sugar levels in patients with type 2 diabetes. It lowers blood sugar in the body by increasing the amount of sugar excreted in the urine. This can lead to side effects like urinary tract infections.

Key Points

  • Canagliflozin, Dapagliflozin
    • Mechanism
      • Sodium-glucose cotransporter inhibitors (SGLT2 Inhibitors)
        • Promotes urinary glucose loss
    • Clinical Uses
      • Hyperglycemia in Type 2 Diabetes Mellitus
        • Taken in combination with control of diet and exercise
    • Side Effects and Adverse Reactions
      • Problems with the urinary tract
        • Cystitis (bladder infection) and other urinary tract infections (UTIs)
        • Urinary urgency & frequency
        • Nocturia
      • Female genital infections
        • Vaginal candidiasis