Isotretinoin
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Summary
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Key Points
- Isotretinoin (Accutane)
- Mechanism
- Vitamin A derivative
- Vitamin A supplements should be avoided to avoid toxicity
- Vitamin A derivative
- Clinical Use
- Severe acne
- Used when acne is unresponsive to other treatment
- Severe acne
- Side Effects and Adverse Reactions
- Teratogenic
- Pregnancy category X
- Negative pregnancy test is required before start of treatment
- Use two forms of birth control during treatment
- Patients taking isotretinoin shouldn’t donate blood to avoid the risk of giving blood with the drug to a pregnant woman
- Skin sensitivity
- Dryness of skin, mouth, and eyes
- Skin irritation
- Photosensitivity (sunburn)
- Common, expected side effects
- Muscle damage
- Dizziness
- Headache
- Teratogenic
- Mechanism