Methyldopa
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Maternity Drugs
Summary
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Key Points
- Methyldopa (Aldomet)
- Mechanism
- Alpha-2 adrenergic agonist
- Stimulates alpha-adrenergic receptors, leading to a decreased blood pressure
- Same drug class as clonidine, and has several of the same side effects
- Alpha-2 adrenergic agonist
- Clinical Use
- Hypertension
- Used to treat hypertension during pregnancy and gestational hypertension
- Preeclampsia
- First line therapy for mild preeclampsia
- Preeclampsia is severely high blood pressure that occurs after week 20 in pregnancy in women who otherwise have normal blood pressure. It can be life threatening if not managed.
- Hypertension
- Side Effects and Adverse Reactions
- Dizziness
- Drowsiness
- Dry mouth
- Peripheral edema
- Anxiety
- Depression
- Headache
- Fever
- Mechanism