Medicine & USMLE

Pilocarpine

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Other Drugs
  1. Isotretinoin
  2. Pilocarpine

Summary

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Key Points

  • Pilocarpine (Pilocar, Isopto Carpine)
    • Mechanism
      • Cholinergic Drug
        • Mimics the effect of acetylcholine
    • Clinical Uses
      • Glaucoma
        • Constricts the pupils (miosis), opening the Schlemm canal and thus promoting drainage of aqueous humor (fluid)
        • Decreases ocular pressure
      • Xerostomia (dry mouth)
        • When given orally
    • Side Effects and Adverse Reactions
      • Cholinergic Side Effects
        • Systemic side effects are not very common when given via eye drops but symptoms of systemic absorption include:
          • Urinary frequency
          • Diarrhea
          • Lacrimation
          • Diaphoresis
          • Bradycardia
          • Hypotension