Medicine & USMLE

Phenazopyridine

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GU Drugs
  1. Phenazopyridine

Summary

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Key Points

  • Phenazopyridine
    • Mechanism
      • Analgesic
        • Contains an azo dye that, when excreted in the urine, provides a local anesthetic effect on the lining of the urinary tract
        • Should only be taken for 2 days
    • Clinical Use
      • Urinary tract infections
        • Relieves urinary pain, burning, frequency, and urgency associated with a bladder infection
        • Phenazopyridine provides pain relief, but does not treat the infection. The patient will need to additionally take a full course of antibiotics.
      • Other urinary tract pain
        • Surgery
        • Endoscopic procedures
    • Side Effects and Adverse Reactions
      • Red-orange urine discoloration
        • Expected, harmless side effect
        • Other body fluids (tears, saliva, sweat) may also turn a red-orange color
      • Hemolytic anemia
      • Renal dysfunction
      • Hepatic dysfunction