Phenazopyridine
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GU Drugs
Summary
Phenazopyridine is an analgesic drug that relieves pain associated with urinary tract infections. It does not directly treat the infection itself - so it is usually combined with other antibiotics. A harmless side effect of phenazopyridine is red-orange urine discoloration.
Key Points
- Phenazopyridine
- Mechanism
- Analgesic
- Contains an azo dye that, when excreted in the urine, provides a local anesthetic effect on the lining of the urinary tract
- Should only be taken for 2 days
- Analgesic
- Clinical Use
- Urinary tract infections
- Relieves urinary pain, burning, frequency, and urgency associated with a bladder infection
- Phenazopyridine provides pain relief, but does not treat the infection. The patient will need to additionally take a full course of antibiotics.
- Other urinary tract pain
- Surgery
- Endoscopic procedures
- Urinary tract infections
- Side Effects and Adverse Reactions
- Red-orange urine discoloration
- Expected, harmless side effect
- Other body fluids (tears, saliva, sweat) may also turn a red-orange color
- Hemolytic anemia
- Renal dysfunction
- Hepatic dysfunction
- Red-orange urine discoloration
- Mechanism