Guaifenesin

Summary

Guaifenesin, commonly known as Mucinex, is an expectorant, meaning it is a mucus thinner. This makes it useful in treating congestion and productive cough. It should be taken with a full glass of water.

Key Points

• Guaifenesin (Mucinex)
  • Mechanism
    • Expectorant (mucus thinner)
      • Helps thin mucus and other bronchial secretions so they can be eliminated by coughing
      • Should be taken with a full glass of water
        • Taking plenty of fluids will also help thin secretions
  • Clinical Use
    • Cough and Congestion
      • Pneumonia with productive cough
      • Bronchitis
      • The common cold
      • Often combined with antitussives (e.g. dextromethorphan) or decongestants
      • Assess the cough type and mucus characteristics
  • Side Effects and Adverse Reactions
    • GI upset
    • Drowsiness, dizziness
    • Headache