Medicine & USMLE

Scopolamine

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Neuro Drugs
  1. Levodopa, Carbidopa
  2. Levetiracetam
  3. Valproic Acid
  4. Anticholinergic Syndrome
  5. Cholinergic Crisis
  6. Benztropine / Trihexyphenidyl
  7. Lidocaine
  8. Pyridostigmine, Neostigmine, Edrophonium
  9. Naltrexone
  10. Pregabalin
  11. Scopolamine
  12. Phenytoin
  13. Ethosuximide
  14. Succinylcholine
  15. Memantine
  16. Donepezil
  17. Halothane / Flurane
  18. Propofol
  19. Ergotamine
  20. Triptans
  21. Selegiline / Rasagiline
  22. Entacapone / Tolcapone
  23. Gabapentin
  24. Lamotrigine
  25. Carbamazepine
  26. Ramelteon

Summary

Scopolamine is an anticholinergic medication that is used to treat motion sickness and reduce oral secretions. As an anticholinergic drug, it causes anticholinergic side effects like urinary retention, constipation, dry mouth, and pupillary dilation.

Key Points

  • Scopolamine
    • Mechanism
      • Anticholinergic
        • Blocks the effects of acetylcholine on the CNS
    • Clinical Use
      • Vestibular Nausea (motion sickness)
        • Meniere’s Disease
          • An inner ear disorder that causes dizziness and nausea
        • Often given via a transdermal patch, placed behind the ear, that lasts 3 days. Patch should be placed 4 hours before the desired effect.
      • Reduces airway secretions
        • Anesthesia/intubation
        • Death rattle
    • Side Effects and Adverse Reactions
      • Anticholinergic Effects
        • Dry mouth (xerostomia)
        • Blurred vision from pupil dilation
          • Contraindicated in glaucoma
        • Constipation
        • Urinary retention
        • Tachycardia
        • Hypotension