Succinylcholine
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Neuro Drugs
- Levodopa, Carbidopa
- Levetiracetam
- Valproic Acid
- Anticholinergic Syndrome
- Cholinergic Crisis
- Benztropine / Trihexyphenidyl
- Lidocaine
- Pyridostigmine, Neostigmine, Edrophonium
- Naltrexone
- Pregabalin
- Scopolamine
- Phenytoin
- Ethosuximide
- Succinylcholine
- Opioids
- Memantine
- Halothane / Flurane
- Donepezil
- Propofol
- Ergotamine
- Triptans
- Selegiline / Rasagiline
- Entacapone / Tolcapone
- Gabapentin
- Lamotrigine
- Carbamazepine
- Ramelteon
Summary
Succinylcholine is a muscle paralytic drug that is given alongside anesthesia during surgery. Its most dangerous side effect is malignant hyperthermia.
Key Points
- Succinylcholine
- Mechanism
- Depolarizing Neuromuscular Blocker
- Blocks repolarization of the muscle cells, preventing them from contracting
- Depolarizing Neuromuscular Blocker
- Clinical Use
- Muscle relaxant/paralytic
- Used as an adjunct in anesthesia to paralyze the muscles of the oropharynx during intubation to prevent gag reflex and aspiration
- Control seizures during electroconvulsive therapy (ECT)
- Muscle relaxant/paralytic
- Side Effects and Adverse Reactions
- Malignant hyperthermia
- Medical emergency; excessive release of calcium in muscles causes sustained muscle contractions
- Characterized by high fever, muscle rigidity
- Respiratory depression
- Bradycardia
- Malignant hyperthermia
- Mechanism