Medicine & USMLE

Halothane / Flurane

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Neuro Drugs
  1. Levodopa, Carbidopa
  2. Levetiracetam
  3. Valproic Acid
  4. Anticholinergic Syndrome
  5. Cholinergic Crisis
  6. Benztropine / Trihexyphenidyl
  7. Lidocaine
  8. Pyridostigmine, Neostigmine, Edrophonium
  9. Naltrexone
  10. Pregabalin
  11. Scopolamine
  12. Phenytoin
  13. Ethosuximide
  14. Succinylcholine
  15. Memantine
  16. Donepezil
  17. Halothane / Flurane
  18. Propofol
  19. Ergotamine
  20. Triptans
  21. Selegiline / Rasagiline
  22. Entacapone / Tolcapone
  23. Gabapentin
  24. Lamotrigine
  25. Carbamazepine
  26. Ramelteon

Summary

Halothane and fluranes are inhaled anesthetic drugs used for general anesthesia. They have the serious adverse effect of causing malignant hyperthermia. Halothane can also cause hepatotoxicity, so liver enzymes should be closely monitored.

Key Points

  • Halothane, Fluranes
    • Mechanism
      • Inhaled Anesthetic
        • Depresses CNS through unclear mechanism
    • Clinical Use
      • General Anesthesia
        • Inhaled anesthetic that can also cause muscle relaxation
    • Side Effects and Adverse Reactions
      • Malignant hyperthermia
      • Hepatotoxicity (with halothane)
      • Respiratory depression
      • Hypotension
        • Secondary to cardiovascular depression