Medicine & USMLE

Halothane / Flurane

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Neuro Drugs
  1. Anticholinergic Syndrome
  2. Cholinergic Crisis
  3. Benztropine / Trihexyphenidyl
  4. Pyridostigmine, Neostigmine, Edrophonium
  5. Donepezil
  6. Memantine
  7. Scopolamine
  8. Levodopa, Carbidopa
  9. Selegiline / Rasagiline
  10. Entacapone / Tolcapone
  11. Propofol
  12. Halothane / Flurane
  13. Opioids
  14. Succinylcholine
  15. Lidocaine
  16. Ergotamine
  17. Triptans
  18. Pregabalin
  19. Gabapentin
  20. Ramelteon

Summary

Halothane and fluranes are inhaled anesthetic drugs used for general anesthesia. They have the serious adverse effect of causing malignant hyperthermia. Halothane can also cause hepatotoxicity, so liver enzymes should be closely monitored.

Key Points

  • Halothane, Fluranes
    • Mechanism
      • Inhaled Anesthetic
        • Depresses CNS through unclear mechanism
    • Clinical Use
      • General Anesthesia
        • Inhaled anesthetic that can also cause muscle relaxation
    • Side Effects and Adverse Reactions
      • Malignant hyperthermia
      • Hepatotoxicity (with halothane)
      • Respiratory depression
      • Hypotension
        • Secondary to cardiovascular depression