USMLE

Gabapentin

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Neuro Drugs
  1. Pyridostigmine, Neostigmine, Edrophonium
  2. Valproic Acid
  3. Naltrexone
  4. Levetiracetam
  5. Pregabalin
  6. Scopolamine
  7. Phenytoin
  8. Ethosuximide
  9. Levodopa, Carbidopa
  10. Succinylcholine
  11. Memantine
  12. Donepezil
  13. Halothane / Flurane
  14. Propofol
  15. Ergotamine
  16. Triptans
  17. Selegiline / Rasagiline
  18. Entacapone / Tolcapone
  19. Gabapentin
  20. Lamotrigine
  21. Carbamazepine
  22. Mannitol
  23. Ramelteon

Summary

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Key Points

  • Gabapentin (Neurontin)
    • Mechanism
      • Drug class: Anticonvulsant/Antiseizure
        • Inhibits spontaneous neuron firing by inhibiting the calcium channels
    • Clinical Use
      • Neuropathic pain
        • Diabetic neuropathy
        • Postherpetic neuralgia (neuropathic pain following shingles)
      • Partial seizures
      • Migraine headaches
      • Bipolar disorder
      • Menopausal symptoms
    • Side Effects and Adverse Reactions
      • Sedation/Drowsiness
        • Closely monitor older adults, as the sedative effects may increase their risk for falls
        • Educate patients not to drive until they know how the medication effects them
      • Ataxia
      • Dizziness