Ergotamine
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Neuro Drugs
- Levodopa, Carbidopa
- Levetiracetam
- Valproic Acid
- Anticholinergic Syndrome
- Cholinergic Crisis
- Benztropine / Trihexyphenidyl
- Lidocaine
- Pyridostigmine, Neostigmine, Edrophonium
- Naltrexone
- Pregabalin
- Scopolamine
- Phenytoin
- Ethosuximide
- Succinylcholine
- Opioids
- Memantine
- Halothane / Flurane
- Donepezil
- Propofol
- Ergotamine
- Triptans
- Selegiline / Rasagiline
- Entacapone / Tolcapone
- Gabapentin
- Lamotrigine
- Carbamazepine
- Ramelteon
Summary
Ergotamine is a medication that causes vasoconstriction to treat migraine headaches. It is not a regularly scheduled drug, but is rather taken at the onset of the migraine.
Key Points
- Ergotamine (Ergomar)
- Mechanism
- Ergot alkaloids
- Block adrenergic receptors, causing peripheral vasoconstriction
- Ergot alkaloids
- Clinical Use
- Migraines
- Often combined with caffeine
- Should be administered at the onset of aura or headache
- Migraines
- Side Effects and Adverse Reactions
- Contraindicated with vasospasm (e.g. Prinzmetal angina, Raynaud phenomenon)
- Gastrointestinal distress
- Nausea, vomiting
- Physical dependence
- Is not intended to be taken daily, only at the onset of a migraine headache
- Withdrawal symptoms include migraine-like symptoms (headache, nausea, vomiting, restlessness)
- Teratogenic
- Pregnancy Category X
- Mechanism