Medicine & USMLE

Memantine

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Neuro Drugs
  1. Levodopa, Carbidopa
  2. Levetiracetam
  3. Valproic Acid
  4. Anticholinergic Syndrome
  5. Cholinergic Crisis
  6. Benztropine / Trihexyphenidyl
  7. Lidocaine
  8. Pyridostigmine, Neostigmine, Edrophonium
  9. Naltrexone
  10. Pregabalin
  11. Scopolamine
  12. Phenytoin
  13. Ethosuximide
  14. Succinylcholine
  15. Opioids
  16. Memantine
  17. Halothane / Flurane
  18. Donepezil
  19. Propofol
  20. Ergotamine
  21. Triptans
  22. Selegiline / Rasagiline
  23. Entacapone / Tolcapone
  24. Gabapentin
  25. Lamotrigine
  26. Carbamazepine
  27. Ramelteon

Summary

Memantine is a medication that is used to treat Alzheimer Disease. This medication offers a symptomatic benefit by improving the cognition of patients, but cannot cure nor reverse the course of disease.

Key Points

  • Memantine (Namenda)
    • Mechanism
      • NMDA receptor antagonist
        • Binds to NMDA receptors, blocking the neurotransmitter glutamate which then prevents calcium from building up in the brain cells.
    • Clinical Uses
      • Alzheimer Disease
        • Memantine is not a cure, but slows the progression of the disease
    • Side Effects and Adverse Reactions
      • Stevens Johnson Syndrome
        • Report symptoms of a rash immediately
      • Sedation, drowsiness
      • Dizziness
      • Constipation
      • Headaches