USMLE

Lamotrigine

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Neuro Drugs
  1. Pyridostigmine, Neostigmine, Edrophonium
  2. Valproic Acid
  3. Naltrexone
  4. Levetiracetam
  5. Pregabalin
  6. Scopolamine
  7. Phenytoin
  8. Ethosuximide
  9. Levodopa, Carbidopa
  10. Succinylcholine
  11. Memantine
  12. Donepezil
  13. Halothane / Flurane
  14. Propofol
  15. Ergotamine
  16. Triptans
  17. Selegiline / Rasagiline
  18. Entacapone / Tolcapone
  19. Gabapentin
  20. Lamotrigine
  21. Carbamazepine
  22. Mannitol
  23. Ramelteon

Summary

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Key Points

  • Lamotrigine (Lamictal)
    • Mechanism
      • Drug class: Anticonvulsants/Anti Seizure
        • Blocks voltage-gated sodium channels
    • Clinical Use
      • Seizures
        • Can treat partial and generalized seizures
      • Bipolar disorder
        • First line treatment
    • Side Effects and Adverse Reactions
      • Rash / Stevens-Johnson Syndrome
        • Any signs of a rash should be immediately reported to the provider
      • Sedation, fatigue, dizziness
        • Acts to depress CNS activity at sodium channels
      • Gastrointestinal distress
        • May be taken with food to reduce GI distress