Lamotrigine
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Neuro Drugs
- Levodopa, Carbidopa
- Levetiracetam
- Valproic Acid
- Anticholinergic Syndrome
- Cholinergic Crisis
- Benztropine / Trihexyphenidyl
- Lidocaine
- Pyridostigmine, Neostigmine, Edrophonium
- Naltrexone
- Pregabalin
- Scopolamine
- Phenytoin
- Ethosuximide
- Succinylcholine
- Opioids
- Memantine
- Halothane / Flurane
- Donepezil
- Propofol
- Ergotamine
- Triptans
- Selegiline / Rasagiline
- Entacapone / Tolcapone
- Gabapentin
- Lamotrigine
- Carbamazepine
- Ramelteon
Summary
Lamotrigine is a medication used to treat seizures as well as bipolar disorder. An important adverse effect is a life-threatening drug rash called Stevens-Johnson Syndrome, so any signs of a rash should be reported immediately. Another common side effect is drowsiness or sedation.
Key Points
- Lamotrigine (Lamictal)
- Mechanism
- Drug class: Anticonvulsants/Anti Seizure
- Blocks voltage-gated sodium channels
- Drug class: Anticonvulsants/Anti Seizure
- Clinical Use
- Seizures
- Can treat partial and generalized seizures
- Bipolar disorder
- First line treatment
- Seizures
- Side Effects and Adverse Reactions
- Rash / Stevens-Johnson Syndrome
- Any signs of a rash should be immediately reported to the provider
- Sedation, fatigue, dizziness
- Acts to depress CNS activity at sodium channels
- Gastrointestinal distress
- May be taken with food to reduce GI distress
- Rash / Stevens-Johnson Syndrome
- Mechanism