Imatinib

19

Summary

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Key Points

  • Imatinib, nilotinib, dasatinib
    • Mechanism
      • Tyrosine kinase inhibitor
        • Targets BCR-ABL fusion protein that is the cause of certain cancers like CML
    • Clinical Uses
      • Cancer / Chemotherapy
        • Chronic myeloid leukemia (CML)
        • Acute Lymphoblastic leukemia (ALL)
    • Side Effects and Adverse Reactions
      • Edema and fluid retention