Summary

Coming soon...

Key Points

• Pioglitazone
  • Mechanism
    • Thiazolidinediones
      • Decrease insulin resistance and increase blood glucose control
      • Carry a low risk for hypoglycemia (similar to metformin)
  • Clinical Uses
    • Hyperglycemia in Type 2 Diabetes Mellitus
  • Side Effects and Adverse Reactions
    • Cardiovascular Toxicity
      • Myocardial Infarction
      • Heart Failure
        • Can worsen pre-existing heart failure by causing fluid retention
    • Bladder Cancer