Long Acting Insulin
545 views
Anti-Diabetic Drugs
- Insulin Overview
- Rapid Acting Insulin
- Short Acting Insulin
- Intermediate Acting Insulin
- Long Acting Insulin
- Metformin
- Sulfonylureas
- Canagliflozin
- Pioglitazone
Summary
Long-acting insulins include the drugs glargine and detemir. Long acting insulins are given once daily, have no peak, and instead work steadily over a duration of around 24 hours. Long acting insulins cannot be mixed; they must be given in their own syringe.
Key Points
- Long Acting Insulin
- Drug Names
- Glargine (Lantus)
- Detemir (Levemir)
- Onset, Peak, Duration
- Onset = 1-2 hours
- Peak = ~1 day (no peak)
- Exact peak for detemir depends on patient and ranges from 4-9 hours
- Glargine’s peak is so slow and long (>12 h) that there is no apparent peak in dose
- Duration = up to 24 hours
- Nursing Considerations
- Cannot be mixed
- Never mix long-acting insulins with other insulin formulations (e.g. regular insulin)
- Inject once daily, at the same time each day
- Given to prevent, not correct, hyperglycemia
- Long peak is intended to counteract baseline production of glucose by liver
- Cannot be mixed
- Drug Names