Intermediate Acting Insulin
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Anti-Diabetic Drugs
- Insulin Overview
- Rapid Acting Insulin
- Short Acting Insulin
- Intermediate Acting Insulin
- Long Acting Insulin
- Metformin
- Sulfonylureas
- Canagliflozin
- Pioglitazone
Summary
Intermediate acting insulin formulations include NPH insulin. This type of insulin works slower than rapid or short-acting insulins but faster than long-acting insulins, with a peak time averaging around 5 hours after administration. Remember that NPH has a cloudy appearance and that when mixed with regular insulin, it should be drawn up in the syringe last, after regular insulin has already been drawn.
Key Points
- Intermediate Acting Insulin
- Drug Names
- NPH (Humulin N, Novolin N)
- Onset, Peak, Duration
- Onset = 1.5-4 hours
- Peak = ~5 hours
- Exact peak depends on patient and ranges from 4-12 hours
- Duration = 12-18 hours
- Nursing Considerations
- “Cloudy” in appearance
- When mixing with Regular insulin, draw NPH insulin LAST
- Clear before cloudy, or “RN” - regular before NPH
- Drug Names