Medicine & USMLE

Oseltamivir

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Anti-Infective Drugs
  1. Vancomycin
  2. Metronidazole
  3. Penicillins
  4. Cephalosporins
  5. Macrolides
  6. Fluoroquinolones
  7. Aminoglycosides
  8. Tetracyclines
  9. Sulfonamides
  10. Rifampin
  11. Isoniazid
  12. Ethambutol
  13. Chloroquine
  14. Acyclovir
  15. Oseltamivir
  16. Azoles
  17. Nystatin
  18. Amphotericin B

Summary

Oseltamivir, better known by its trade name Tamiflu, is an antiviral medication that is used to treat influenza virus or the common flu. It’s main side effect is GI upset.

Key Points

  • Oseltamivir (Tamiflu)
    • Mechanism
      • Antiviral
        • Neuraminidase inhibitors
          • Decreases the viral spread by inhibiting the neuraminidase glycoprotein in the virus-infected cells
    • Clinical Use
      • Influenza (flu)
        • Effective against both influenza A and B
          • Has been proven to reduce the length of the flu symptoms by several days
        • Treatment should begin within 48 hours of onset of flu symptoms
        • May also be used as influenza prophylaxis within 48 hours of exposure
    • Side Effects and Adverse Reactions
      • GI distress
        • Nausea, vomiting
        • Medication may be taken with food to minimize GI discomfort
      • Dizziness, vertigo, fatigue
      • Headache
      • Insomnia