Glutamine, often abbreviated as the 3-letters Gln or the 1-letter Q, is one of the 20 amino acids that make up proteins in our body. Glutamine’s R-group consists of an amide at the end of a long, 2-carbon chain. This amide group makes glutamine a polar, hydrophilic amino acid that dissolves easily in water. Finally, glutamine is neutral or uncharged at physiological pH.

Key Points

  • Glutamine
    • Abbreviations 
      • Gln, Q
    • Chemical Structure
    • R group: -CH2-CH2-Amide
      • Amide
        • Contrast vs. Glutamate (which has carboxyl instead of amide)
      • 2 bridging methylene carbons (-CH2-CH2-)
        • Contrast vs. Asparagine (which has only 1 bridging carbon)
    • Polarity
      • Polar (water soluble/hydrophilic)
    • Charge at pH 7
      • Neutral (0)