USMLE

Glutamine

1,673 views
Amino Acids
  1. Serine
  2. Asparagine
  3. Alanine
  4. Valine
  5. Leucine
  6. Isoleucine
  7. Phenylalanine
  8. Tryptophan
  9. Methionine
  10. Proline
  11. Glycine
  12. Threonine
  13. Cysteine
  14. Tyrosine
  15. Glutamine
  16. Aspartate
  17. Glutamate
  18. Histidine
  19. Lysine
  20. Arginine

Summary

Glutamine, often abbreviated as the 3-letters Gln or the 1-letter Q, is one of the 20 amino acids that make up proteins in our body. Glutamine’s R-group consists of an amide at the end of a long, 2-carbon chain. This amide group makes glutamine a polar, hydrophilic amino acid that dissolves easily in water. Finally, glutamine is neutral or uncharged at physiological pH.

Key Points

  • Glutamine
    • Abbreviations 
      • Gln, Q
    • Chemical Structure
    • R group: -CH2-CH2-Amide
      • Amide
        • Contrast vs. Glutamate (which has carboxyl instead of amide)
      • 2 bridging methylene carbons (-CH2-CH2-)
        • Contrast vs. Asparagine (which has only 1 bridging carbon)
    • Polarity
      • Polar (water soluble/hydrophilic)
    • Charge at pH 7
      • Neutral (0)