USMLE

Asparagine

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Amino Acids
  1. Serine
  2. Asparagine
  3. Alanine
  4. Valine
  5. Leucine
  6. Isoleucine
  7. Phenylalanine
  8. Tryptophan
  9. Methionine
  10. Proline
  11. Glycine
  12. Threonine
  13. Cysteine
  14. Tyrosine
  15. Glutamine
  16. Aspartate
  17. Glutamate
  18. Histidine
  19. Lysine
  20. Arginine

Summary

Asparagine is one of the 20 amino acids that make up proteins in our body, and it is often abbreviated as the 3-letter Asn or single letter N. Asparagine’s R-group consists of an amide at the end of a short, 1 carbon bridge. This amide makes asparagine a polar or hydrophilic amino acid that dissolves easily in water. Finally, asparagine is neutral or uncharged at physiological pH.

Key Points

  • Asparagine
    • Abbreviations 
      • Asn, N
    • Chemical Structure
    • R group: -CH2-Amide
      • Amide
        • Contrast vs. Aspartate (which has carboxyl instead of amide)
      • 1 bridging methylene carbon (-CH2-)
        • Contrast vs. Glutamine (which has 2 bridging carbons)
    • Polarity
      • Polar (water soluble/hydrophilic)
    • Charge at pH 7
      • Neutral (0)