USMLE

5th Generation Cephalosporins

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Antibiotics / Antiparasitics
  1. Penicillin Overview
  2. Penicillinase-Sensitive vs. Penicillinase-Resistant Penicillins
  3. Anti-Pseudomonal Penicillins
  4. Cephalosporins Overview
  5. 1st Generation Cephalosporins
  6. 2nd Generation Cephalosporins
  7. 3rd Generation Cephalosporins
  8. 4th Generation Cephalosporins
  9. 5th Generation Cephalosporins
  10. Carbapenems
  11. Monobactams (Aztreonam)
  12. Vancomycin
  13. Aminoglycosides
  14. Tetracyclines
  15. Tigecycline
  16. Chloramphenicol
  17. Clindamycin
  18. Linezolid
  19. Macrolides
  20. Polymyxins
  21. Sulfonamides
  22. Dapsone
  23. Trimethoprim
  24. Fluoroquinolones
  25. Daptomycin
  26. Metronidazole
  27. Rifamycins (Rifampin, Rifabutin)
  28. Isoniazid
  29. Pyrazinamide
  30. Ethambutol
  31. Chloroquine

Summary

Fifth generation cephalosporins are a class of antibiotics that includes the drug ceftaroline. While ceftaroline has broad spectrum coverage against gram-positive and gram-negative bacteria, it is generally clinically reserved as one of the only effective treatments against MRSA, or methicillin-resistant staph aureus.

Key Points

  • 5th Generation Cephalosporins
    • Drug Names
      • CefTAROLINE
    • Mechanism
      • Same as other Cephalosporins (see: Cephalosporin Overview)
    • Clinical Use
      • Broad gram positive and negative coverage
        • MRSA and E. faecalis
      • Does NOT cover Pseudomonas aeruginosa
    • Adverse Effects
      • Same as other Cephalosporins (see: Cephalosporin Overview)