4th Generation Cephalosporins

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Summary

Fourth generation cephalosporins are beta-lactam antibiotics that are relatively newer cephalosporin drugs. The most important fourth-generation cephalosporin to know is cefepime. Cefepime as a fourth-generation cephalosporin has broad coverage against both gram positive and gram negative bacteria. Importantly, fourth generation cephalosporins like cefepime can be used to treat pseudomonas infections.

Key Points

  • 4th Generation Cephalosporins
    • Drug Names
      • CefePIME
    • Mechanism
      • Same as other Cephalosporins (see: Cephalosporin Overview)
    • Clinical Use
      • Broad gram positive and negative coverage
        • Pseudomonas aeruginosa
    • Adverse Effects
      • Same as other Cephalosporins (see: Cephalosporin Overview)