4th Generation Cephalosporins
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Antibiotics / Antiparasitics
- Penicillin Overview
- Penicillinase-Sensitive vs. Penicillinase-Resistant Penicillins
- Anti-Pseudomonal Penicillins
- Cephalosporins Overview
- 1st Generation Cephalosporins
- 2nd Generation Cephalosporins
- 3rd Generation Cephalosporins
- 4th Generation Cephalosporins
- 5th Generation Cephalosporins
- Carbapenems
- Monobactams (Aztreonam)
- Vancomycin
- Aminoglycosides
- Tetracyclines
- Tigecycline
- Chloramphenicol
- Clindamycin
- Linezolid
- Macrolides
- Polymyxins
- Sulfonamides
- Dapsone
- Trimethoprim
- Fluoroquinolones
- Daptomycin
- Metronidazole
- Rifamycins (Rifampin, Rifabutin)
- Isoniazid
- Pyrazinamide
- Ethambutol
- Chloroquine
Summary
Fourth generation cephalosporins are beta-lactam antibiotics that are relatively newer cephalosporin drugs. The most important fourth-generation cephalosporin to know is cefepime. Cefepime as a fourth-generation cephalosporin has broad coverage against both gram positive and gram negative bacteria. Importantly, fourth generation cephalosporins like cefepime can be used to treat pseudomonas infections.
Key Points
- 4th Generation Cephalosporins
- Drug Names
- CefePIME
- Mechanism
- Same as other Cephalosporins (see: Cephalosporin Overview)
- Clinical Use
- Broad gram positive and negative coverage
- Pseudomonas aeruginosa
- Broad gram positive and negative coverage
- Adverse Effects
- Same as other Cephalosporins (see: Cephalosporin Overview)
- Drug Names