Hydralazine

49

Summary

Coming soon...

Key Points

  • Mechanism
    • Vasodilator
      • Relaxes the blood vessels, allowing for vasodilation and thus lowering the blood pressure
    • Clinical Use
      • Severe hypertension, acute onset
        • Hypertension with preeclampsia
        • Hypertensive crisis
      • Heart failure
        • Used in combination with a nitrate
    • Side Effects and Adverse Reactions
      • Hypotension
        • Reflex tachycardia
          • Often given in conjunction with beta blockers to prevent against reflex tachycardia
          • Can commonly lead to palpitations
          • Heart rate and blood pressure should be monitored before every administration
        • Dizziness
      • Hepatotoxicity
      • Headache
      • GI distress
        • Nausea/vomiting, diarrhea, anorexia
        • GI bleeding