Medicine & USMLE


Cardiovascular Drugs
  1. Beta Blockers
  2. ACE Inhibitors
  3. Angiotensin II Receptor Blockers (ARBs)
  4. Adenosine
  5. Atropine
  6. Amiodarone
  7. DHP Calcium Channel Blockers
  8. Non-DHP Calcium Channel Blockers
  9. Clonidine
  10. Clopidogrel
  11. Digoxin
  12. Dopamine
  13. Epinephrine
  14. Hydralazine
  15. Nitroglycerin
  16. Norepinephrine
  17. Statins


Clopidogrel, also known by its trade name Plavix, is an antiplatelet drug that works to prevent the formation of blood clots. The prevention of clots is useful in preventing thrombotic diseases caused by clots like myocardial infarctions and strokes. Side effects of clopidogrel include bleeding and thrombocytopenia.

Key Points

  • Class and Mechanism
    • Antiplatelet
      • Inhibits platelet aggregation and prevents ADP from binding with the ADP receptor
      • Prevents clot formation
    • Clinical Use
      •  Thromboembolism prophylaxis
        • Myocardial infarction (MI)
        • Stroke
    • Side Effects and Adverse Reactions
      • Bleeding
        • discontinue 7 days before surgery
        • Due to inhibition of platelet function and potential thrombocytopenia (low platelet count)
        • Contraindicated in patients with any active bleeding, peptic ulcers, etc.
        • Carefully monitor for any signs/symptoms of bleeding
      • Hypotension
      • GI effects
        • Diarrhea, dyspepsia, abdominal pain