Tizanidine
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Summary
Tizanidine is an alpha-2 activating drug used to treat muscle spasms in a variety of conditions. Side effects of tizanidine include hypotension.
Key Points
- Tizanidine
- Mechanism
- Centrally-acting alpha-2 receptor agonist
- Related to clonidine, but less effective on modulating sympathetic outflow to heart and blood vessels
- Centrally-acting alpha-2 receptor agonist
- Indications
- Muscle spasticity (antispasmodic)
- Mechanism for relief is unclear
- e.g. Multiple sclerosis, ALS, Cerebral Palsy
- Muscle spasticity (antispasmodic)
- Side Effects
- Hypotension
- Mechanism