USMLE

Leptin

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Endocrine & Hormones
  1. Leptin
  2. Ghrelin
  3. Protein Hormones
  4. Steroid Hormones
  5. Insulin
  6. Diabetes
  7. Glucagon
  8. Epinephrine
  9. Cortisol
  10. Thyroid Hormones
  11. Calcitonin
  12. Parathyroid Hormone (PTH)
  13. Anterior Pituitary
  14. Prolactin
  15. Luteinizing Hormone (LH)
  16. Follicle-Stimulating Hormone (FSH)
  17. Growth Hormone (GH)
  18. Posterior Pituitary

Summary

Leptin is a hormone produced by fat cells, or adipocytes, in response to high blood lipid levels. Leptin targets the hypothalamus to suppress appetite and cause a feeling of “fullness.”

Key Points

  • Leptin
    • Origin: Adipose tissue 
      • Trigger: High blood lipid levels 
    • Target: Hypothalamus
    • Effect: Binds to and inhibits receptors
      • Indicates “fullness”