Ramelteon
4,520 views
Other Neuro Pharm
- Ramelteon
- Triptans
- Benzodiazepines - Function
- Zolpidem Zaleplon Eszopiclone
- Suvorexant
- Bromocriptine (Ergot Dopamine Agonists)
- Pramipexole, Ropinirole
- Amantadine
- Levodopa, Carbidopa
- Entacapone, Tolcapone
- Selegiline and Rasagiline
- Benztropine, Trihexyphenidyl
- Tetrabenazine
- Baclofen
- Memantine
- Riluzole
- Full Opioid Agonists
- Partial Opioid Agonists
- Dextromethorphan
- Tramadol
- Naloxone
- Naltrexone
Summary
Ramelteon is a drug used to promote sleep. It is an agonist of melatonin receptors in the suprachiasmatic nucleus of the hypothalamus. By inducing sleep, ramelteon is useful as a hypnotic for the treatment of insomnia. There’s a few nonspecific side effects of ramelteon, including dizziness, nausea, fatigue, and headaches. Finally, ramelteon does not cause dependence so it's generally safer to use compared to other sleep-promoting drugs like the benzodiazepines!
Key Points
- Ramelteon
- Mechanism
- Melatonin receptor agonist (hence the mel in the name)
- Binds MT1 and MT2 in suprachiasmatic nucleus
- Melatonin receptor agonist (hence the mel in the name)
- Clinical Use
- Treats Insomnia
- Adverse effects
- Dizziness
- Nausea
- Fatigue
- Headache
- No dependence (not a controlled substance)
- Mechanism