Follicular Phase
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Reproductive
Follicular Phase
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Summary
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Key Points
- Follicular Phase
- Part of the menstrual cycle from development of the oocyte up until ovulation
- Typically lasts ~16 days
- (Primary) Follicle develops around Oocyte
- Granulosa Cells stimulated by FSH
- Zona Pellucida is a non-cellular layer of glycoproteins secreted by Granulosa Cells around the oocyte
- Induce maturation of the Oocyte
- Theca Cells stimulated by LH
- Produce estrogen
- LH stimulation causes theca cells to make androgens (e.g. testosterone), which are converted into estrogens by granulosa cells under the stimulation of FSH
- Stimulate uterine wall growth
- Estrogen stimulates uterine wall growth in preparation for implantation and pregnancy
- Negative feedback loop of estrogen inhibits LH release
- Produce estrogen
- Granulosa Cells stimulated by FSH
- Ends in Ovulation
- The egg is released into the Fallopian Tube
- Part of the menstrual cycle from development of the oocyte up until ovulation