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Picornavirus Overview

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Key Points

  • Picornaviruses
    • Characteristics
      • RNA virus
        • replicate in the cytoplasm of cells
        • Single-stranded
      • + sense
      • Linear chromosome
      • RNA translated into 1 large polypeptide which is cleaved into functional viral proteins
        • Cleavage by virus encoded proteases
      • No envelope
        • Are not destroyed by the gut
      • Icosahedral capsid