Adenovirus
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Viruses - DNA Viruses
- Herpesvirus Overview
- Herpes Simplex Virus 1 (HSV1)
- Herpes Simplex Virus 2 (HSV2)
- Varicella-Zoster Virus (HHV3)
- Epstein-Barr Virus (HHV4)
- Cytomegalovirus (HHV5)
- Human Herpesviruses 6 and 7 (HHV6 and HHV7)
- Human Herpesviruses 8 (HHV8)
- Poxvirus
- Hepadnavirus
- Adenovirus
- Papillomavirus (HPV)
- Polyomavirus
- Parvovirus
Key Points
- Adenovirus
- Characteristics
- DNA virus
- Replicates in nucleus
- Double-stranded
- No envelope
- Linear chromosome
- DNA virus
- Transmission
- Multiple routes
- Droplets, fecal oral, contact, etc.
- Seen in crowded/close quarters
- E.g. daycare centers, public swimming pools, military barracks, summer camp
- Multiple routes
- Presentation
- Pharyngoconjunctival fever
- Pharyngitis (sore throat)
- Most common cause of tonsillitis in young children
- May be accompanied by cervical lymphadenopathy
- Conjunctivitis (pink eye)
- Outbreaks in swimming pools/lakes
- Cervical lymphadenopathy may be seen
- Fever (non-specific)
- Pharyngitis (sore throat)
- Acute hemorrhagic cystitis
- Presents with bloody urine (hematuria)
- Painful urination (dysuria) may also be seen
- Most common cause of outbreaks in children
- Pneumonia
- Gastroenteritis
- May present with a diarrheal illness in children
- May cause myocarditis in children
- Pharyngoconjunctival fever
- Diagnosis
- Viral culture/PCR is used
- Treatment
- Supportive; self-limiting
- Cidofovir may be used in patients with immunosuppression or severe disease
- Supportive; self-limiting
- Characteristics