Summary

Coming soon...

Key Points

• Luteinizing Hormone (LH)
  • Type: Peptide
  • Origin: Anterior Pituitary
  • Trigger: Stimulation by GnRH from hypothalamus
    • GnRH = Gonadotropin Releasing Hormone
  • Target: Testes and Ovaries
    • Effect: Stimulates release of
      • Testosterone from testes
      • Estradiol/Estrogen from ovaries
      • Testosterone and Estradiol are androgens involved in reproduction as well as the development of secondary sex characteristics (i.e. body hair, breast and genital growth, etc)
  • Feedback:
    • Estradiol usually inhibits LH release through negative feedback
    • Exception: Luteal Surge
      • During ovulation, Estradiol increases LH release through positive feedback
        • This causes spikes in both Estradiol and LH, which in turn causes ovulation.