Luteinizing Hormone (LH)
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Endocrine & Hormones
- Leptin
- Ghrelin
- Protein Hormones
- Steroid Hormones
- Insulin
- Diabetes
- Glucagon
- Epinephrine
- Cortisol
- Thyroid Hormones
- Calcitonin
- Parathyroid Hormone (PTH)
- Anterior Pituitary
- Prolactin
- Luteinizing Hormone (LH)
- Follicle-Stimulating Hormone (FSH)
- Growth Hormone (GH)
- Posterior Pituitary
Summary
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Key Points
- Luteinizing Hormone (LH)
- Type: Peptide
- Origin: Anterior Pituitary
- Trigger: Stimulation by GnRH from hypothalamus
- GnRH = Gonadotropin Releasing Hormone
- Target: Testes and Ovaries
- Effect: Stimulates release of
- Testosterone from testes
- Estradiol/Estrogen from ovaries
- Testosterone and Estradiol are sex hormones involved in reproduction as well as the development of secondary sex characteristics (i.e. body hair, breast and genital growth, etc)
- Effect: Stimulates release of
- Feedback:
- Estradiol usually inhibits LH release through negative feedback
- Exception: Luteal Surge
- During ovulation, Estradiol increases LH release through positive feedback
- This causes spikes in both Estradiol and LH, which in turn causes ovulation.
- During ovulation, Estradiol increases LH release through positive feedback