Growth Hormone (GH)

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Summary

Growth hormone, or GH for short, is a protein hormone produced by the anterior pituitary gland. The anterior pituitary gland produces growth hormone, in response to upstream stimulation by growth-hormone releasing hormone or GHRH from the hypothalamus. Downstream, growth hormone targets muscle and bone cells to stimulate muscle and bone growth.

Key Points

  • Growth Hormone (GH)
    • Type: Peptide
    • Origin: Anterior Pituitary
    • Trigger: Stimulation by GHRH from hypothalamus
      • GHRH = Growth Hormone Releasing Hormone
    • Target: Muscle and Bone
      • GH targets a variety of cells throughout the body. Muscle and bone are two prominent examples.
      • Effect: Stimulates growth
        • Increases:
          • Rate of mitosis
          • Cell size
          • Rate of transcription/translation