USMLE

Varenicline

1,372 views
Psych Pharm
  1. Lithium
  2. Typical Antipsychotics
  3. Atypical Antipsychotics
  4. SSRIs
  5. SNRIs
  6. Tricyclic Antidepressants (TCAs)
  7. Monoamine Oxidase Inhibitors (MAOIs)
  8. Buproprion
  9. Mirtazapine
  10. Trazadone
  11. Vilazodone
  12. Vortioxetine
  13. Buspirone
  14. Varenicline

Summary

Varenicline is a drug that works as a partial agonist at nicotinic receptors. It is primarily used to treat nicotine withdrawal in patients who are quitting smoking.

Key Points

  • Varenicline
    • Mechanism of Action:
      • Partial Agonist of Nicotinic Receptor
    • Clinical Use:
      • Smoking Cessation
        • Reduces nicotine cravings - useful for nicotine withdrawal
    • Adverse Effects:
      • Toxicity: Sleep disturbance, depressed mood