Anaplasma vs. Ehrlichia
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Bacteria - Gram Negative
- Neisseria spp: Overview
- Neisseria gonorrhoeae
- Neisseria meningitidis
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- Chlamydia: Overview
- Chlamydia trachomatis
- Chlamydia pneumoniae vs. psittaci
- Rickettsia rickettsii
- Rickettsia typhi vs. prowazekii
- Anaplasma vs. Ehrlichia
- Coxiella burnetii (Q fever)
Anaplasma vs. Ehrlichia
- Characteristics
- Obligate intracellular
- Grow inside vacuoles in human and animal WBCs
- Obligate intracellular
- Vectors
- Tick
- Anaplasma: Ixodes tick
- Ehrlichia: Lone Star tick
- Tick
- Presentation
- Non-specific flu-like illness (fever, chills, malaise, myalgia, headache)
- Ehrlichia: Rash may occur
- Contrast vs. Anaplasma, which does not present with rash
- Histology
- morulae (mulberry-like inclusions) in cytoplasm
- Anaplasma: grows inside granulocytes (neutrophils)
- Ehrlichia: grows inside monocytes (macrophages)
- morulae (mulberry-like inclusions) in cytoplasm
- Treatment
- Doxycycline is first-line
- Rifampin or chloramphenicol are second line when tetracyclines are not tolerated
- Doxycycline is first-line