Neisseria meningitidis
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Bacteria - Gram Negative
- Neisseria spp: Overview
- Neisseria gonorrhoeae
- Neisseria meningitidis
- Haemophilus influenzae
- Bordetella pertussis
- Brucella
- Legionella pneumophila
- Pseudomonas aeruginosa: Overview
- Pseudomonas aeruginosa: Disease
- Salmonella Overview
- Salmonella typhi
- Salmonella enteritidis
- Shigella
- Yersinia enterocolitica
- Escherichia coli: Overview
- Enterohemorrhagic E. Coli (EHEC)
- Enterotoxigenic E. Coli (ETEC)
- Klebsiella pneumoniae
- Campylobacter jejuni
- Vibrio spp.
- Helicobacter pylori
- Borrelia burgdorferi (Lyme Disease)
- Leptospira interrogans
- Treponema pallidum: Overview
- Treponema pallidum: Diagnosis
- Congenital syphilis
- Chlamydia: Overview
- Chlamydia trachomatis
- Chlamydia pneumoniae vs. psittaci
- Rickettsia rickettsii
- Rickettsia typhi vs. prowazekii
- Anaplasma vs. Ehrlichia
- Coxiella burnetii (Q fever)
Neisseria meningitidis
- Unique Characteristics
- See Neisseria Overview for characteristics to all Neisseria spp.
- Polysaccharide capsule
- Increased risk in asplenic patients, since spleen works to remove encapsulated organisms
- Contrast vs. N gonorrhoeae - no capsule
- Maltose acid detection
- Contrast vs. N gonorrhoeae - no maltose acid detection
- Transmitted via respiratory droplets/direct contact
- Common in college students and military, between people in close proximity
- Presentation
- Meningitis
- Adrenal hemorrhage (Waterhouse-Friderichsen syndrome)
- Seen in disseminated infection (septicemia)
- Presents with adrenal insufficiency, fever, DIC (bleeding), shock
- Fever, chills
- Vaccine
- Available for at-risk individuals
- Does not cover all serogroups (e.g. Group B)
- Contrast vs. N gonorrhoeae - no vaccine
- Treatment
- Penicillin G
- First-line agent for treatment of active infection (without meningitis)
- Not useful for prophylaxis (use rifampin)
- Ceftriaxone
- First-line for bacterial meningitis
- Rifampin for prevention in close contacts
- Penicillin G