Neisseria gonorrhoeae
6,706 views
Bacteria - Gram Negative
- Neisseria spp: Overview
- Neisseria gonorrhoeae
- Neisseria meningitidis
- Haemophilus influenzae
- Bordetella pertussis
- Brucella
- Legionella pneumophila
- Pseudomonas aeruginosa: Overview
- Pseudomonas aeruginosa: Disease
- Salmonella Overview
- Salmonella typhi
- Salmonella enteritidis
- Shigella
- Yersinia enterocolitica
- Escherichia coli: Overview
- Enterohemorrhagic E. Coli (EHEC)
- Enterotoxigenic E. Coli (ETEC)
- Klebsiella pneumoniae
- Campylobacter jejuni
- Vibrio spp.
- Helicobacter pylori
- Borrelia burgdorferi (Lyme Disease)
- Leptospira interrogans
- Treponema pallidum: Overview
- Treponema pallidum: Diagnosis
- Congenital syphilis
- Chlamydia: Overview
- Chlamydia trachomatis
- Chlamydia pneumoniae vs. psittaci
- Rickettsia rickettsii
- Rickettsia typhi vs. prowazekii
- Anaplasma vs. Ehrlichia
- Coxiella burnetii (Q fever)
Neisseria gonorrhoeae
- Unique Characteristics
- See Neisseria Overview for characteristics to all Neisseria spp.
- No polysaccharide capsule
- Contrast vs. N meningitidis - polysaccharide capsule present
- No maltose acid detection
- Contrast vs. N meningitidis - maltose acid detection
- Sexually-transmitted
- Second most common STI in US (after Chlamydia)
- May also be perinatally transmitted
- Disease: Gonorrhea
- Urethritis/cervicitis
- Dysuria
- Purulent discharge
- Contrast with Chlamydia, which has watery discharge
- Pelvic inflammatory disease (PID)
- Occur with poor treatment of initial infection
- Fitz-Hugh-Curtis syndrome
- Perihepatitis - infection and inflammation of liver capsule
- “Violin string” adhesions of peritoneum to liver
- Septic arthritis
- Staph aureus is the most common cause of septic arthritis, but suspect N. gonorrhoeae in sexually active young adults, especially IV drug users
- Arthritis, pharyngitis, dermatitis, tenosynovitis may also be seen in disseminated gonorrheal infections
- Neonatal conjunctivitis (2- 5 days after birth) in perinatal infections
- Urethritis/cervicitis
- Treatment
- Ceftriaxone
- Intramuscular injection of ceftriaxone is first-line for gonococcal infections
- must treat for chlamydia coinfection with azithromycin or doxycycline
- Inadequate treatment can result in PID and future infertility or other complications (ectopic pregnancy)
- Erythromycin eye ointment prevents neonatal blindness
- Ceftriaxone