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Glomerulus

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  • Glomerulus 
    • Tuft of capillaries separated by a thin layer of cells from Bowman’s space/capsule
      • Collectively referred to as the renal corpuscle.
      • The layers of cells (epithelia) serve as a filter.
    • Filtration of blood produces filtrate
      • Hydrostatic pressure drives fluid from blood (capillaries) into filtrate (capsular space)
        • Filtration rate is called GFR (glomerular filtration rate)
          • Increased with higher systemic blood pressure
          • Increased with more blood flow
            • Circulating blood enters via afferent arteriole and exits through the efferent arteriole.
      • Large molecules like proteins and cells are prevented from entering filtrate