USMLE

Hodgkin Lymphoma

6,235 views
Leukemias and Lymphomas
  1. Acute Myelogenous Leukemia (AML)
  2. Acute Promyelocytic Leukemia (APL)
  3. Acute Lymphocytic Leukemia (ALL)
  4. Chronic Myelogenous Leukemia (CML)
  5. Chronic Lymphocytic Leukemia (CLL)
  6. Hairy Cell Leukemia (HCL)
  7. Hodgkin Lymphoma
  8. Burkitt Lymphoma
  9. Diffuse Large B Cell Lymphoma (DLBCL)
  10. Follicular Lymphoma
  11. Mantle Cell Lymphoma
  12. Marginal Zone Lymphoma
  13. Primary CNS Lymphoma (PCNSL)
  14. Acute T-Cell Leukemia/Lymphoma (ATLL)
  15. Mycosis Fungoides / Sezary Syndrome

Summary

Hodgkin lymphoma is a cancer of lymphocytes characterized by the appearance of Reed-Sternberg Cells on biopsy. Reed-Sternberg cells are cancerous cells with a characteristic “owl-eye” appearance, referring to the presence of two nuclei inside a large cytoplasm. Reed Sternberg cells are also notable for being both CD15 and CD30-positive. Finally, Hodgkin lymphoma is associated with infections with Epstein Barr virus or EBV.