Hodgkin Lymphoma



Hodgkin lymphoma is a cancer of lymphocytes characterized by the appearance of Reed-Sternberg Cells on biopsy. Reed-Sternberg cells are cancerous cells with a characteristic “owl-eye” appearance, referring to the presence of two nuclei inside a large cytoplasm. Reed Sternberg cells are also notable for being both CD15 and CD30-positive. Finally, Hodgkin lymphoma is associated with infections with Epstein Barr virus or EBV.