Hodgkin Lymphoma

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Summary

Hodgkin lymphoma is a cancer of lymphocytes characterized by the appearance of Reed-Sternberg Cells on biopsy. Reed-Sternberg cells are cancerous cells with a characteristic “owl-eye” appearance, referring to the presence of two nuclei inside a large cytoplasm. Reed Sternberg cells are also notable for being both CD15 and CD30-positive. Finally, Hodgkin lymphoma is associated with infections with Epstein Barr virus or EBV.