Marginal Zone Lymphoma
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Leukemias and Lymphomas
- Acute Myelogenous Leukemia (AML)
- Acute Promyelocytic Leukemia (APL)
- Acute Lymphocytic Leukemia (ALL)
- Chronic Myelogenous Leukemia (CML)
- Chronic Lymphocytic Leukemia (CLL)
- Hairy Cell Leukemia (HCL)
- Hodgkin Lymphoma
- Burkitt Lymphoma
- Diffuse Large B Cell Lymphoma (DLBCL)
- Follicular Lymphoma
- Mantle Cell Lymphoma
- Marginal Zone Lymphoma
- Primary CNS Lymphoma (PCNSL)
- Adult T-Cell Leukemia/Lymphoma (ATLL)
- Mycosis Fungoides / Sezary Syndrome
Summary
Marginal Zone Lymphoma is a type of low-grade lymphoma that affects B-cells of the marginal zone of lymphoid tissue. Lymphoid tissue involved can include the spleen, the lymph nodes, as well as extra-nodal mucosal lymph tissue as in the case of MALTomas. Marginal zone lymphoma is associated with a t(11;18) chromosomal translocation. Risk factors for developing marginal zone lymphomas include diseases of chronic inflammation, such as sjogren’s syndrome or hashimoto’s thyroiditis.